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Details on Person PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer

Class:Id	LiteratureReference:8853426
_displayName	PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer
_timestamp	2016-01-22 20:22:00
author	[Person:8853427] Johnson, Emmanuel O [Person:3301992] Chang, Kuei-Hua [Person:8853430] de Pablo, Yolanda [Person:3301976] Ghosh, Soumitra [Person:8853428] Mehta, Rutika [Person:8853434] Badve, Sunil [Person:3301955] Shah, Kavita
created	[InstanceEdit:8853433] Orlic-Milacic, Marija, 2016-01-22
journal	J. Cell. Sci.
pages	2711-22
pubMedIdentifier	21807936
title	PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer
volume	124
year	2011
(literatureReference)	[Reaction:8853429] PHLDA1 binds AURKA [Homo sapiens] [Reaction:8853444] AURKA phosphorylates PHLDA1 [Homo sapiens] [Pathway:8854521] Interaction between PHLDA1 and AURKA [Homo sapiens] [Complex:8853432] AURKA:PHLDA1 [cytosol] [Homo sapiens] [Summation:8853436] Aurora kinase A binds PHLDA1 (TDAG51) and the two proteins c... [Summation:8853441] Aurora kinase A (AURKA) phosphorylates PHLDA1 on serine resi... [CatalystActivityReference:9644009] protein serine/threonine kinase activity of AURKA:PHLDA1 [cytosol] PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer
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