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Details on Person p-6Y-FGFR1(22-763):TACC1(571-805) fusion [plasma membrane]

Class:Id	EntityWithAccessionedSequence:8853142
_displayName	p-6Y-FGFR1(22-763):TACC1(571-805) fusion [plasma membrane]
_timestamp	2025-07-30 21:08:43
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8853143] Rothfels, Karen, 2016-01-21
crossReference	[DatabaseIdentifier:8853120] COSMIC:COSF1362
disease	[Disease:1247632] glioblastoma
endCoordinate	763
hasModifiedResidue	[FragmentInsertionModification:8853111] Insertion of residues 571 to 805 at 764 from UniProt:O75410 TACC1 [ModifiedResidue:2011867] O4'-phospho-L-tyrosine at 463 [ModifiedResidue:2011863] O4'-phospho-L-tyrosine at 583 [ModifiedResidue:2011864] O4'-phospho-L-tyrosine at 585 [ModifiedResidue:2011862] O4'-phospho-L-tyrosine at 653 [ModifiedResidue:2011865] O4'-phospho-L-tyrosine at 654 [ModifiedResidue:2011860] O4'-phospho-L-tyrosine at 730
literatureReference	[LiteratureReference:8853053] Transforming fusions of FGFR and TACC genes in human glioblastoma
modified	[InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30 [InstanceEdit:9962055] Matthews, Lisa, 2025-07-30
name	p-6Y-FGFR1(22-763):TACC1(571-805) fusion
referenceEntity	[ReferenceGeneProduct:402793] UniProt:P11362 FGFR1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8860530] R-HSA-8853142.3
startCoordinate	22
(hasComponent)	[Complex:8853243] p-6Y FGFR1(22-763):TACC1(571-805) fusion dimer [plasma membrane] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905344] Update Tracker - [EntityWithAccessionedSequence:8853142] p-6Y-FGFR1(22-763):TACC1(571-805) fusion [plasma membrane] - v85:[modifyName] [_UpdateTracker:9964885] Update Tracker - [EntityWithAccessionedSequence:8853142] p-6Y-FGFR1(22-763):TACC1(571-805) fusion [plasma membrane] - v94:[add_removeDisease]
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No pathways have been reviewed or authored by p-6Y-FGFR1(22-763):TACC1(571-805) fusion [plasma membrane] (8853142)