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Details on Person PLK1-mediated phosphorylation of GTSE1 is needed for nuclear...
| Class:Id | Summation:8852333 |
|---|---|
| _displayName | PLK1-mediated phosphorylation of GTSE1 is needed for nuclear... |
| _timestamp | 2016-01-15 21:26:44 |
| created | [InstanceEdit:8852334] Orlic-Milacic, Marija, 2016-01-15 |
| modified | [InstanceEdit:8852401] Orlic-Milacic, Marija, 2016-01-15 |
| text | PLK1-mediated phosphorylation of GTSE1 is needed for nuclear accumulation of GTSE1, probably because it exposes the nuclear localization signal (NLS) of GTSE1 to the nuclear import machinery. Nuclear localization of GTSE1 is not needed for normal G2 phase progression, but is needed for the G2 checkpoint recovery (cell cycle re-entry after G2 checkpoint arrest) (Liu et al. 2010). |
| (summation) | [Reaction:8852331] GTSE1 translocates to the nucleus [Homo sapiens] |
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No pathways have been reviewed or authored by PLK1-mediated phosphorylation of GTSE1 is needed for nuclear... (8852333)
