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Details on Person GTSE1 translocates to the nucleus

Class:Id	Reaction:8852331
_displayName	GTSE1 translocates to the nucleus
_doRelease	TRUE
_timestamp	2022-02-08 21:46:02
authored	[InstanceEdit:8852278] Orlic-Milacic, Marija, 2016-01-15
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:8852334] Orlic-Milacic, Marija, 2016-01-15
edited	[InstanceEdit:8852278] Orlic-Milacic, Marija, 2016-01-15
input	[EntityWithAccessionedSequence:8852316] p-S435-GTSE1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8852313] Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery
modified	[InstanceEdit:8855169] Orlic-Milacic, Marija, 2016-02-01 [InstanceEdit:8862043] Orlic-Milacic, Marija, 2016-02-24 [InstanceEdit:9764023] Orlic-Milacic, Marija, 2022-02-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GTSE1 translocates to the nucleus
negativePrecedingEvent	[NegativePrecedingEvent:9764020] Futile Cycle: GTSE1 facilitates proteasome-mediated degradation of TP53
output	[EntityWithAccessionedSequence:8852332] p-S435-GTSE1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:8852317] PLK1 phosphorylates GTSE1 [Homo sapiens] [Reaction:8852324] GTSE1 binds PLK1 [Homo sapiens]
releaseDate	2016-03-23
reviewed	[InstanceEdit:8855167] Bird, Alexander W, 2016-01-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861243] R-HSA-8852331.3
summation	[Summation:8852333] PLK1-mediated phosphorylation of GTSE1 is needed for nuclear...
(hasEvent)	[Pathway:8852276] The role of GTSE1 in G2/M progression after G2 checkpoint [Homo sapiens]
(precedingEvent)	[Reaction:8852337] GTSE1 binds TP53 [Homo sapiens]
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No pathways have been reviewed or authored by GTSE1 translocates to the nucleus (8852331)