Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Phosphorylated GAB1 recruits PI3K to MET

Class:Id	Reaction:8851954
_displayName	Phosphorylated GAB1 recruits PI3K to MET
_doRelease	TRUE
_timestamp	2016-07-19 17:47:24
authored	[InstanceEdit:8876386] Orlic-Milacic, Marija, 2016-06-14
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:8851952] Orlic-Milacic, Marija, 2016-01-12
edited	[InstanceEdit:8876386] Orlic-Milacic, Marija, 2016-06-14
input	[DefinedSet:8851943] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] [Homo sapiens] [Complex:1806218] PIK3CA:PIK3R1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:179899] A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling [LiteratureReference:8851912] Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses
modified	[InstanceEdit:8851958] Orlic-Milacic, Marija, 2016-01-12 [InstanceEdit:8875934] Orlic-Milacic, Marija, 2016-06-09 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8931694] Orlic-Milacic, Marija, 2016-07-18 [InstanceEdit:8931945] Orlic-Milacic, Marija, 2016-07-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylated GAB1 recruits PI3K to MET
output	[Complex:8851953] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:8851933] MET phosphorylates GAB1 [Homo sapiens] [Reaction:8851908] Activated MET binds GAB1 [Homo sapiens] [Reaction:8851919] Activated MET binds GAB1 and GRB2 [Homo sapiens]
releaseDate	2016-09-19
reviewed	[InstanceEdit:8931695] Heynen, Guustaaf, 2016-07-11 [InstanceEdit:8931697] Birchmeier, Walter, 2016-07-11
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8880481] R-HSA-8851954.2
summation	[Summation:8851957] Phosphorylated tyrosine residues Y447, Y472 and Y589 of GAB1...
(hasEvent)	[Pathway:8851907] MET activates PI3K/AKT signaling [Homo sapiens]
(precedingEvent)	[Reaction:8852019] MET bound PI3K generates PIP3 [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by Phosphorylated GAB1 recruits PI3K to MET (8851954)