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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Binding of HIF1A (HIF1-alpha) and/or EPAS1 (HIF2A) to hypoxi...

Class:IdSummation:8848796
_displayNameBinding of HIF1A (HIF1-alpha) and/or EPAS1 (HIF2A) to hypoxi...
_timestamp2016-02-12 14:51:50
created[InstanceEdit:8848799] Orlic-Milacic, Marija, 2015-12-10
modified[InstanceEdit:8848815] Orlic-Milacic, Marija, 2015-12-10
[InstanceEdit:8856939] Orlic-Milacic, Marija, 2016-02-12
textBinding of HIF1A (HIF1-alpha) and/or EPAS1 (HIF2A) to hypoxia response elements (HREs) in the promoter region of the PTK6 (BRK) gene stimulates PTK6 transcription at hypoxia (Regan Anderson et al. 2013). EPAS1 was recently reported to cooperate with the activated glucocorticoid receptor NR3C1 (GCR) and its cofactor PELP1 in the stimulation of PTK6 transcription (Regan Anderson et al. 2016).
(summation)[BlackBoxEvent:8848804] HIF1A,EPAS1 promote PTK6 gene expression [Homo sapiens]
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