Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Phospholipase A (PLA2) hydrolyzes the sn-2 position of phosp...
| Class:Id | Summation:8848555 |
|---|---|
| _displayName | Phospholipase A (PLA2) hydrolyzes the sn-2 position of phosp... |
| _timestamp | 2015-12-16 22:14:42 |
| created | [InstanceEdit:8848554] Rothfels, Karen, 2015-12-09 |
| modified | [InstanceEdit:8849340] Rothfels, Karen, 2015-12-14 [InstanceEdit:8849754] Rothfels, Karen, 2015-12-16 |
| text | Phospholipase A (PLA2) hydrolyzes the sn-2 position of phospholipids, releasing a fatty acid and a lysophospholipid (reviewed in Six and Dennis, 2000; Kudo and Murakami, 2002). A number studies have highlighted roles for a number of PLA2s in the maintenance of Golgi function and structure (de Figueiredo et al, 1998; de Figueiredo et al, 1999). PLAs may generate phospholipid and fatty acid products that recruit effectors of Golgi function and trafficking to the membrane or that affect downstream signaling pathways. Alternately, PLA2s may contribute directly to tubule formation at the Golgi through the production of the membrane-curvature inducing lysophospholipid (reviewed in Bechler et al, 2012). PLA2s may be recruited to the Golgi in response to changes in Ca2+ and/or cargo concentration that occur as a result of secretory traffic (Micaroni et al, 2010; San Pietro et al, 2009; Pulvirenti et al, 2008). |
| (summation) | [Reaction:8848484] PLA2s hydrolyze phospholipids at the Golgi membrane [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Phospholipase A (PLA2) hydrolyzes the sn-2 position of phosp... (8848555)
