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Details on Person PLA2s hydrolyze phospholipids at the Golgi membrane

Class:Id	Reaction:8848484
_displayName	PLA2s hydrolyze phospholipids at the Golgi membrane
_doRelease	TRUE
_timestamp	2016-02-19 18:21:54
authored	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
catalystActivity	[CatalystActivity:8848480] A2-type glycerophospholipase activity of cPLA2s [cytosol]
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:8848482] Rothfels, Karen, 2015-12-08
edited	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
input	[SimpleEntity:29356] H2O [cytosol] [SimpleEntity:429785] PC [Golgi membrane]
isChimeric	FALSE
literatureReference	[LiteratureReference:8848559] The expanding superfamily of phospholipase A(2) enzymes: classification and characterization [LiteratureReference:8848562] Phospholipase A2 enzymes [LiteratureReference:8849278] Evidence that phospholipase A2 activity is required for Golgi complex and trans Golgi network membrane tubulation [LiteratureReference:8849295] Membrane tubule-mediated reassembly and maintenance of the Golgi complex is disrupted by phospholipase A2 antagonists [LiteratureReference:8848553] A PLA1-2 punch regulates the Golgi complex [LiteratureReference:8849691] Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport [LiteratureReference:8849707] Synchronous intra-Golgi transport induces the release of Ca2+ from the Golgi apparatus [LiteratureReference:8849680] A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway
modified	[InstanceEdit:8848563] Rothfels, Karen, 2015-12-09 [InstanceEdit:8849753] Rothfels, Karen, 2015-12-16 [InstanceEdit:8851193] Rothfels, Karen, 2016-01-05 [InstanceEdit:8856718] Rothfels, Karen, 2016-02-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PLA2s hydrolyze phospholipids at the Golgi membrane
output	[SimpleEntity:8848483] 2-lysophosphatidylcholine [Golgi membrane] [SimpleEntity:6814303] fatty acid [cytosol]
releaseDate	2016-03-23
releaseStatus	NEW
reviewed	[InstanceEdit:8855182] Gillespie, Marc E, 2016-02-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8861285] R-HSA-8848484.2
summation	[Summation:8848555] Phospholipase A (PLA2) hydrolyzes the sn-2 position of phosp...
(hasEvent)	[Pathway:6811436] COPI-independent Golgi-to-ER retrograde traffic [Homo sapiens]
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No pathways have been reviewed or authored by PLA2s hydrolyze phospholipids at the Golgi membrane (8848484)