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Details on Person Stearoyl-CoA desaturase 5 (SCD5, also known as acyl-CoA desa...
| Class:Id | Summation:8847585 |
|---|---|
| _displayName | Stearoyl-CoA desaturase 5 (SCD5, also known as acyl-CoA desa... |
| _timestamp | 2016-01-29 14:43:33 |
| created | [InstanceEdit:8847577] D'Eustachio, Peter, 2015-11-30 |
| modified | [InstanceEdit:8854943] D'Eustachio, Peter, 2016-01-29 |
| text | Stearoyl-CoA desaturase 5 (SCD5, also known as acyl-CoA desaturase 4), located on the ER membrane, utilises O2 and electrons from reduced ferrocytochrome b5 (Fe(2+)Cb5) to catalyse the insertion of a double bond into a range of fatty acyl-CoA substrates. SCD5 is most abundant in brain and pancreas. The reaction annotated here shows stearoyl-CoA (ST-CoA) desaturation to oleoyl-CoA (OLE-CoA). Studies of tagged recombinant enzyme overexpressed in transiently transfected cells suggest that the enzyme forms dimers and higher oligomers (Wang et al. 2005; Zhang et al. 2005). |
| (summation) | [Reaction:8847579] SCD5 desaturates ST-CoA to OLE-CoA [Homo sapiens] |
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No pathways have been reviewed or authored by Stearoyl-CoA desaturase 5 (SCD5, also known as acyl-CoA desa... (8847585)
