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Details on Person UniProt:P47941 Crkl
Class:Id
ReferenceGeneProduct:88197
_chainChangeLog
chain:1-303 added on Fri February 6 2015
_displayName
UniProt:P47941 Crkl
_timestamp
2023-11-03 15:01:10
chain
chain:1-303
checksum
A8C801F78EF73573
comment
FUNCTION May mediate the transduction of intracellular signals.SUBUNIT Interacts with DOCK2 and EPOR. Interacts with phosphorylated CBLB and IRS4 (By similarity). Interacts with INPP5D/SHIP1 (PubMed:11031258). Interacts with BCAR1/CAS and NEDD9/HEF1 (By similarity).PTM Phosphorylated on tyrosine. Phosphorylation is prominent during early development, but decreases at later embryonic stages and in newborn mice.SIMILARITY Belongs to the CRK family.
