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Details on Person Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors

Class:IdLiteratureReference:879924
_displayNameMechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors
_timestamp2010-06-25 15:33:55
author[Person:879948] Guthridge, MA
[Person:450044] Stomski, FC
[Person:180595] Thomas, D
[Person:879935] Woodcock, JM
[Person:450025] Bagley, CJ
[Person:140248] Berndt, MC
[Person:450033] Lopez, Angel
created[InstanceEdit:879892] Jupe, S, 2010-06-25
journalStem Cells
pages301-13
pubMedIdentifier9766809
titleMechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors
volume16
year1998
(literatureReference)[Summation:879946] Upon ligand binding to the alpha subunit, the alpha and Bc s...
[Summation:879950] Activated JAK2 binds to unphosphorylated STAT5; cytokine tre...
[Summation:879964] The receptors for GM-CSF, IL-3, and IL-5 all consist of a li...
[Summation:893524] Phosphorylation of the receptor common beta chain (Bc) creat...
[Pathway:512988] Interleukin-3, Interleukin-5 and GM-CSF signaling [Homo sapiens]
[BlackBoxEvent:879942] The receptor is activated [Homo sapiens]
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