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Details on Person The interaction of IL-3 with the receptor leads to the activ...

Class:IdSummation:879913
_displayNameThe interaction of IL-3 with the receptor leads to the activ...
_timestamp2010-07-23 17:44:20
created[InstanceEdit:879892] Jupe, S, 2010-06-25
modified[InstanceEdit:893547] Jupe, S, 2010-07-01
[InstanceEdit:904809] Jupe, S, 2010-07-02
[InstanceEdit:914066] Jupe, S, 2010-07-21
[InstanceEdit:914195] Jupe, S, 2010-07-23
textThe interaction of IL-3 with the receptor leads to the activation of SRC tyrosine kinase activity. The exact nature of this stimulation is unclear but it appears independent of JAK2 (Chaturvedi et al. 1998) and has the outcome that activated SRC binds and tyrosine phosphorylates STAT3.
(summation)[BlackBoxEvent:879923] SRC is activated [Homo sapiens]
[BlackBoxEvent:914045] Src is activated [Mus musculus]
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No pathways have been reviewed or authored by The interaction of IL-3 with the receptor leads to the activ... (879913)