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Details on Person AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation

Class:IdLiteratureReference:879775
_displayNameAMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
_timestamp2010-06-23 01:56:23
author[Person:879736] Lamia, KA
[Person:879740] Sachdeva, UM
[Person:879708] DiTacchio, L
[Person:879800] Williams, EC
[Person:879747] Alvarez, JG
[Person:447076] Egan, DF
[Person:447072] Vasquez, DS
[Person:879714] Juguilon, H
[Person:549494] Panda, S
[Person:380962] Shaw, RJ
[Person:140401] Thompson, CB
[Person:879799] Evans, RM
created[InstanceEdit:879757] May, B, 2010-06-23
journalScience
pages437-40
pubMedIdentifier19833968
titleAMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
volume326
year2009
(literatureReference)[Complex:9859658] Fbxl3:p-S71,S280-Cry1 [nucleoplasm] [Mus musculus]
[Reaction:9859662] Ampk phosphorylates Cry1 on serine-71 and serine-280 [Mus musculus]
[Reaction:9859664] Fbxl3 binds p-S71,S280-Cry1 [Mus musculus]
[Pathway:9859713] Regulation of the circadian clock [Homo sapiens]
[Pathway:9909396] Circadian clock [Homo sapiens]
[Reaction:9932519] Fbxl3:Cul1:Skp1:Rbx1 binds phosphorylated Cry1,2 [Mus musculus]
[BlackBoxEvent:9934892] Proteolysis of K48polyUb,p-S-Cry1,2 [Mus musculus]
[Pathway:9983885] AMP and AMPK regulate the circadian clock [Homo sapiens]
[Summation:9984170] In the presence of AMP, AMPK phosphorylates serine-71 and se...
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