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Details on Person AGER binds ERK1/2

Class:Id	Reaction:879362
_displayName	AGER binds ERK1/2
_doRelease	TRUE
_timestamp	2010-12-02 14:34:07
authored	[InstanceEdit:849794] Jupe, S, 2010-06-01
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:879462] Jupe, S, 2010-06-17
edited	[InstanceEdit:1020099] Jupe, S, 2010-11-16
inferredFrom	[Reaction:997411] AGER binds rat ERK1/2 [Homo sapiens]
input	[Complex:879365] AGER ligands:AGER [plasma membrane] [Homo sapiens] [DefinedSet:169291] MAPKs [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:879440] The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site
modified	[InstanceEdit:997391] Jupe, S, 2010-11-09 [InstanceEdit:997401] Jupe, S, 2010-11-09 [InstanceEdit:1020100] Jupe, S, 2010-11-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	AGER binds ERK1/2
output	[Complex:879427] AGER ligands:AGER:ERK [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:879411] Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor [Homo sapiens] [Reaction:879377] The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:997390] Yan, SD, 2010-11-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104472] R-HSA-879362.2
summation	[Summation:997396] Binding of ligand to AGER results in the activation of multi...
(hasEvent)	[Pathway:879415] Advanced glycosylation endproduct receptor signaling [Homo sapiens]
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No pathways have been reviewed or authored by AGER binds ERK1/2 (879362)