Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person dsDNA:Aim2 clusters bind Asc

Class:IdReaction:877385
_displayNamedsDNA:Aim2 clusters bind Asc
_doReleaseTRUE
_timestamp2016-11-15 14:21:24
authored[InstanceEdit:877366] Jupe, S, 2010-06-14
compartment[Compartment:70101] cytosol
created[InstanceEdit:877390] Jupe, S, 2010-06-14
edited[InstanceEdit:1253354] Jupe, S, 2011-04-28
input[Complex:877389] dsDNA:Aim2 oligomer [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:877391] Asc [cytosol] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:874032] AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
[LiteratureReference:874003] AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
modified[InstanceEdit:1253356] Jupe, S, 2011-04-28
[InstanceEdit:1254262] Jupe, S, 2011-04-28
[InstanceEdit:8948662] Matthews, Lisa, 2016-11-15
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namedsDNA:Aim2 clusters bind Asc
output[Complex:877397] dsDNA:Aim2 oligomer:Asc [cytosol] [Mus musculus]
releaseDate2011-06-14
reviewed[InstanceEdit:1253355] Kufer, TA, 2011-04-28
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:1357658] R-MMU-877385.3
summation[Summation:877392] dsDNA:AIM2 clusters bind ASC via a PYD-PYD interaction.
(inferredFrom)[Reaction:844620] dsDNA:AIM2 clusters bind ASC [Homo sapiens]
(precedingEvent)[Reaction:877388] dsDNA:AIM2:ASC cluster binds procaspase-1 [Mus musculus]
[Change default viewing format]
No pathways have been reviewed or authored by dsDNA:Aim2 clusters bind Asc (877385)