Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person TYK2 [cytosol]

Class:IdEntityWithAccessionedSequence:877348
_displayNameTYK2 [cytosol]
_timestamp2010-12-02 14:50:59
compartment[Compartment:70101] cytosol
created[InstanceEdit:877344] Garapati, P V, 2010-06-14
endCoordinate1187
nameTYK2
Non-receptor tyrosine-protein kinase TYK2
TYK2_HUMAN
referenceEntity[ReferenceGeneProduct:66635] UniProt:P29597 TYK2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1108246] R-HSA-877348.1
startCoordinate1
(hasCandidate)[CandidateSet:1067656] JAK1, JAK2, (TYK2) [cytosol] [Homo sapiens]
[CandidateSet:6784370] JAK1,TYK2 [cytosol] [Homo sapiens]
(hasComponent)[Complex:909708] IFNAR1:TYK2 [plasma membrane] [Homo sapiens]
[Complex:6784360] IL10RB:TYK2 [plasma membrane] [Homo sapiens]
[Complex:6785829] IL13RA1:TYK2 [plasma membrane] [Homo sapiens]
[Complex:8950046] IL12RB1:TYK2 [plasma membrane] [Homo sapiens]
[Complex:8983338] IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3:TYK2 [cytosol] [Homo sapiens]
(input)[Reaction:6785762] IL13RA1 binds TYK2 [Homo sapiens]
[Reaction:8950057] IL12RB1 binds TYK2 [Homo sapiens]
[BlackBoxEvent:8983386] NORELEASE_NEED+EVIDENCE_IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 binds TYK2 [Homo sapiens]
[Reaction:8987223] IL10RB binds TYK2 [Homo sapiens]
[BlackBoxEvent:9676071] CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK [Homo sapiens]
[Reaction:9851114] NPM1-ALK-dependent TYK2 phosphorylation [Homo sapiens]
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No pathways have been reviewed or authored by TYK2 [cytosol] (877348)