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Query author contributions in Reactome

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Details on Person ATP:P2X7 oligomer:PANX1 heptamer [plasma membrane]

Class:IdComplex:877242
_displayNameATP:P2X7 oligomer:PANX1 heptamer [plasma membrane]
_timestamp2024-03-29 00:48:08
compartment[Compartment:876] plasma membrane
created[InstanceEdit:877211] Jupe, S, 2010-06-11
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:874011] Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor
[LiteratureReference:9905957] P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes
[LiteratureReference:9905971] Potential role for a specialized β3 integrin-based structure on osteocyte processes in bone mechanosensation
modified[InstanceEdit:1306809] Jupe, S, 2011-05-27
[InstanceEdit:2213009] Matthews, L, 2012-04-27
[InstanceEdit:9892589] May, Bruce, 2024-03-28
[InstanceEdit:9905992] May, Bruce, 2024-03-29
nameATP:P2X7 oligomer:PANX1 heptamer
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1358210] R-HSA-877242.2
(hasMember)[DefinedSet:9905947] P2RX7:PANX1,ATP:P2RX7:PANX1 [plasma membrane] [Homo sapiens]
(output)[BlackBoxEvent:877198] P2X7 mediates membrane pores that include pannexin-1 [Homo sapiens]
[Reaction:9905952] ATP binds P2RX7 in P2RX7 trimer:PANX1 heptamer [Homo sapiens]
(physicalEntity)[CatalystActivity:9855115] monoatomic anion channel activity of ATP:P2X7 oligomer:PANX1 heptamer [plasma membrane]
[CatalystActivity:9905926] extracellularly ATP-gated monoatomic cation channel activity of ATP:P2X7 oligomer:PANX1 heptamer [plasma membrane]
(updatedInstance)[_UpdateTracker:9872170] Update Tracker - [Complex:877242] ATP:P2X7 oligomer:Pannexin-1 [plasma membrane] - v41:[removeCompartment, updateContainedComponent]
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No pathways have been reviewed or authored by ATP:P2X7 oligomer:PANX1 heptamer [plasma membrane] (877242)
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