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Details on Person P2X7 forms oligomeric non-selective cation channels

Class:Id	Reaction:877158
_displayName	P2X7 forms oligomeric non-selective cation channels
_doRelease	TRUE
_timestamp	2011-06-10 08:48:01
authored	[InstanceEdit:622270] Jupe, S, 2010-04-22
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:877211] Jupe, S, 2010-06-11
edited	[InstanceEdit:1253354] Jupe, S, 2011-04-28
inferredFrom	[Reaction:877248] p2x7 forms oligomeric non-selective cation channels [Rattus norvegicus]
input	[Complex:877166] ATP:P2X7 [plasma membrane] [Homo sapiens] [Complex:877166] ATP:P2X7 [plasma membrane] [Homo sapiens] [Complex:877166] ATP:P2X7 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:925457] Jupe, S, 2010-08-06 [InstanceEdit:1253356] Jupe, S, 2011-04-28 [InstanceEdit:1254262] Jupe, S, 2011-04-28 [InstanceEdit:1317415] D'Eustachio, P, 2011-06-01 [InstanceEdit:1361858] Jupe, S, 2011-06-06 [InstanceEdit:1361865] Jupe, S, 2011-06-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	P2X7 forms oligomeric non-selective cation channels
output	[Complex:877257] ATP:P2X7 oligomer [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:877178] ATP binds to P2X7 [Homo sapiens]
releaseDate	2011-06-14
reviewed	[InstanceEdit:1253355] Kufer, TA, 2011-04-28 [InstanceEdit:1361863] Rittinger, K, 2011-06-06 [InstanceEdit:1361862] Wong, Edmond, 2011-06-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1357647] R-HSA-877158.2
summation	[Summation:877221] At low to intermediate concentrations of extracellular ATP, ...
(hasEvent)	[Pathway:844456] The NLRP3 inflammasome [Homo sapiens]
(precedingEvent)	[Reaction:877187] P2X7 mediates loss of intracellular K+ [Homo sapiens] [BlackBoxEvent:877198] P2X7 mediates membrane pores that include pannexin-1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9777492] Update Tracker - [Reaction:877158] P2X7 forms oligomeric non-selective cation channels - v71:[modifyText]
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No pathways have been reviewed or authored by P2X7 forms oligomeric non-selective cation channels (877158)