Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:Q9Y324 FCF1

Class:IdReferenceGeneProduct:87674
_chainChangeLogchain:1-198 added on Fri February 6 2015
_displayNameUniProt:Q9Y324 FCF1
_timestamp2026-02-20 22:21:25
chainchain:1-198
checksumA0C98414C21F16AE
commentFUNCTION Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.SUBUNIT Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.SUBCELLULAR LOCATION Belongs to the UTP23/FCF1 family. FCF1 subfamily.
descriptionrecommendedName: rRNA-processing protein FCF1 homolog
geneNameFCF1
C14orf111
CGI-35
identifierQ9Y324
isSequenceChangedFALSE
keyword3D-structure
Nucleus
Proteomics identification
Reference proteome
Ribosome biogenesis
rRNA processing
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
[InstanceEdit:9983091] Weiser, Joel, 2026-02-20
nameFCF1
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8999482] ENSEMBL:ENSG00000119616 FCF1 [Homo sapiens]
secondaryIdentifierFCF1_HUMAN
Q86TW8
Q8TBL8
sequenceLength198
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:6790672] FCF1 [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q9Y324 FCF1 (87674)