THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE.
WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE
Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q9JJG7 Caln1
Class:Id
ReferenceGeneProduct:87545
_chainChangeLog
chain:1-219 added on Fri February 6 2015;chain:1-219 for 87545 removed on Wed February 17 2021;chain:1-261 for 87545 added on Wed February 17 2021
_displayName
UniProt:Q9JJG7 Caln1
_timestamp
2023-11-03 18:22:06
chain
chain:1-261
checksum
D38AE0DFBBAE38D9
comment
FUNCTION Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.SUBUNIT Interacts with PI4KB. This binding competes with FREQ/NCS1 binding in a calcium-dependent manner.SUBCELLULAR LOCATION Brain-specific. High expression in the cerebellum, hippocampus, and cortex.DEVELOPMENTAL STAGE Shows little prenatal expression, with highest expression at postnatal day 21.DOMAIN The C-terminal transmembrane domain (TMD) is necessary and sufficient for membrane targeting.SEQUENCE CAUTION Truncated N-terminus.
description
recommendedName: Calcium-binding protein 8 shortName: CaBP8 alternativeName: Calneuron I alternativeName: Calneuron-1
