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Details on Person AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Class:IdLiteratureReference:874032
_displayNameAIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
_timestamp2010-06-09 16:32:35
author[Person:141890] Fernandes-Alnemri, T
[Person:873949] Yu, JW
[Person:141886] Datta, P
[Person:507963] Wu, J
[Person:141891] Alnemri, ES
created[InstanceEdit:874056] Jupe, S, 2010-06-09
journalNature
pages509-13
pubMedIdentifier19158676
titleAIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
volume458
year2009
(literatureReference)[Summation:844616] AIM2 binds to cytosolic dsDNA via its C-terminal HIN domain....
[Summation:874077] AIM2 oligomerizes, forming AIM2 clusters that are able to in...
[Reaction:844619] AIM2 binds dsDNA [Homo sapiens]
[Reaction:877385] dsDNA:Aim2 clusters bind Asc [Mus musculus]
[Reaction:877388] dsDNA:AIM2:ASC cluster binds procaspase-1 [Mus musculus]
[Polymerisation:877396] Aim2 oligomerizes [Mus musculus]
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