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Details on Person Binding of STAT1 to p-IFNGR1

Class:Id	Reaction:873921
_displayName	Binding of STAT1 to p-IFNGR1
_doRelease	TRUE
_timestamp	2021-09-24 21:00:10
authored	[InstanceEdit:873929] Garapati, P V, 2010-06-08
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:873929] Garapati, P V, 2010-06-08
edited	[InstanceEdit:909728] Garapati, P V, 2010-07-07
input	[Complex:873814] IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:380745] STAT1-1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:380745] STAT1-1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:507782] Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process [LiteratureReference:873881] Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91) [LiteratureReference:933486] A road map for those who don't know JAK-STAT
modified	[InstanceEdit:913528] Garapati, P V, 2010-07-16 [InstanceEdit:933346] Garapati, P V, 2010-08-10 [InstanceEdit:933518] Garapati, P V, 2010-08-16 [InstanceEdit:933763] Garapati, P V, 2010-08-17 [InstanceEdit:941856] Garapati, P V, 2010-09-06 [InstanceEdit:994080] Garapati, P V, 2010-11-05 [InstanceEdit:998146] Garapati, P V, 2010-11-09 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9754418] Orlic-Milacic, Marija, 2021-09-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Binding of STAT1 to p-IFNGR1
negativePrecedingEvent	[NegativePrecedingEvent:9754409] Futile Cycle: Release of STAT1 dimer from active receptor unit
output	[Complex:873828] STAT1 bound to p-IFNGR1 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:873924] Phosphorylation of IFNGR1 by JAK kinases [Homo sapiens] [Reaction:873918] Transphosphorylation of JAK1 [Homo sapiens]
releaseDate	2010-12-14
reviewed	[InstanceEdit:933762] Abdul-Sater, AA, Schindler, C, 2010-08-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104594] R-HSA-873921.3
summation	[Summation:873835] The phosphorylated tyrosine residue 440 in the 440YDKPH444 m...
(hasEvent)	[Pathway:877300] Interferon gamma signaling [Homo sapiens]
(precedingEvent)	[Reaction:873922] Phosphorylation of STAT1 by JAK kinases [Homo sapiens]
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No pathways have been reviewed or authored by Binding of STAT1 to p-IFNGR1 (873921)