Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person SOCS3 [cytosol]

Class:IdEntityWithAccessionedSequence:873794
_displayNameSOCS3 [cytosol]
_timestamp2010-12-02 15:00:16
compartment[Compartment:70101] cytosol
created[InstanceEdit:873796] Garapati, P V, 2010-06-08
endCoordinate225
nameSOCS3
Suppressor of cytokine signaling 3
SOCS3_HUMAN
referenceEntity[ReferenceGeneProduct:64814] UniProt:O14543 SOCS3 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1110957] R-HSA-873794.1
startCoordinate1
(hasComponent)[Complex:1112718] Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] [Homo sapiens]
[Complex:2672301] LEP:p-LEPR:p-JAK2:SOCS3 [plasma membrane] [Homo sapiens]
[Complex:8848108] p-Y342-PTK6:SOCS3 [cytosol] [Homo sapiens]
[Complex:9729683] SOCS3:ELOB:ELOC:CUL5:RNF7 [cytosol] [Homo sapiens]
(hasMember)[DefinedSet:877267] SOCS-1 and SOCS-3 [cytosol] [Homo sapiens]
[DefinedSet:1169189] CIS, SOCS1-3 [cytosol] [Homo sapiens]
[CandidateSet:1169199] SOCS [cytosol] [Homo sapiens]
[DefinedSet:6790032] STAT3-upregulated cytosolic proteins [cytosol] [Homo sapiens]
[DefinedSet:8863155] CUL5-box protein [cytosol] [Homo sapiens]
(input)[Reaction:1112755] SOCS3 binds IL6ST [Homo sapiens]
[Reaction:2672302] Phosphorylated LEPR Binds SOCS3 [Homo sapiens]
[Reaction:8848110] SOCS3 binds activated PTK6 [Homo sapiens]
(output)[BlackBoxEvent:8848178] STAT3 stimulates SOCS3 expression [Homo sapiens]
[BlackBoxEvent:8955885] SOCS3 gene expression is inhibited by RUNX1 [Homo sapiens]
[BlackBoxEvent:9705458] p-Y-STAT1,3,5 dimer enhances expression of SOCS3 [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by SOCS3 [cytosol] (873794)