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Details on Person The metalloproteinase Tolloid (TLD) cleaves Short gastrulati...

Class:IdSummation:870750
_displayNameThe metalloproteinase Tolloid (TLD) cleaves Short gastrulati...
_timestamp2010-06-08 13:06:02
created[InstanceEdit:870763] Williams, MG, 2010-06-08
textThe metalloproteinase Tolloid (TLD) cleaves Short gastrulation (SOG) protein resulting in the dissociation of ligand dimer from SOG and Twisted gastrulation (TSG) protein. The free ligand dimer, Decapentaplegic (DPP), Screw (SCW) and the DPP:SCW heterodimer, is now at liberty to interact with appropriate receptors located at the plasma membrane.
(summation)[Reaction:209029] TLD cleaves SOG and the DPP/SCW dimer complex dissociates [Drosophila melanogaster]
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