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Details on Person FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

Class:Id	LiteratureReference:870464
_displayName	FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
_timestamp	2010-06-08 12:40:19
author	[Person:870507] Dupont, S [Person:870557] Mamidi, A [Person:870509] Cordenonsi, M [Person:870485] Montagner, M [Person:870476] Zacchigna, L [Person:870508] Adorno, M [Person:870473] Martello, G [Person:870549] Stinchfield, MJ [Person:870470] Soligo, S [Person:870558] Morsut, L [Person:416759] Inui, M [Person:508023] Moro, S [Person:870543] Modena, N [Person:870537] Argenton, F [Person:870528] Newfeld, SJ [Person:870559] Piccolo, S
created	[InstanceEdit:870527] Williams, MG, 2010-06-08
journal	Cell
pages	123-35
pubMedIdentifier	19135894
title	FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
volume	136
year	2009
(literatureReference)	[Summation:870447] SMAD4 monoubiquitinated by TRIM33 translocates from the nucl... [Summation:870468] E3 ubiquitin protein ligase TRIM33 (also known as Ecto, Ecto... [Summation:870486] In the cytosol, a ubiquitin hydrolase USP9X (FAM) binds to u... [Summation:870566] USP9X (FAM) deubiquitinates SMAD4, thereby opposing the nega... [Summation:2167866] TRIM33 (also known as Ecto, Ectodermin or Tif1-gamma) monoub... [Summation:2190612] In the nucleus, SMAD2/3:SMAD4 heterotrimer complex acts as a... [Summation:2190619] Transcriptional activity of SMAD2/3:SMAD4 heterotrimer can b... [Summation:5696537] USP9X specifically hydrolyzes both Lys-29- and Lys-33-linked... [Reaction:870437] USP9X (FAM) deubiquitinates SMAD4 [Homo sapiens] [Reaction:870449] TRIM33 monoubiquitinates SMAD4 [Homo sapiens] List all 16 refering instances
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No pathways have been reviewed or authored by FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination (870464)