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Details on Person UniProt:Q9V407 Axn

Class:IdReferenceGeneProduct:85721
_chainChangeLogchain:1-745 added on Sat February 7 2015
_displayNameUniProt:Q9V407 Axn
_timestamp2023-11-03 15:25:07
chainchain:1-745
checksum31A502528CEE84BA
commentFUNCTION Inhibitor of the WG signaling pathway. Down-regulates beta-catenin (armadillo=ARM). Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (zeste-white 3=ZW3).SUBUNIT Interacts with ZW3 and ARM. The interaction between AXN and ARM occurs via the armadillo repeats contained in ARM.SUBCELLULAR LOCATION Ubiquitously expressed throughout the development.
descriptionrecommendedName: Axin alternativeName: Axis inhibition protein alternativeName: d-Axin shortName: dAxin
geneNameAxn
CG7926
identifierQ9V407
isSequenceChangedFALSE
keywordCytoplasm
Developmental protein
Phosphoprotein
Reference proteome
Wnt signaling pathway
modified[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618410] Weiser, JD
[InstanceEdit:5618413] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameAxn
referenceDatabase[ReferenceDatabase:2] UniProt
secondaryIdentifierAXN_DROME
Q9XYC1
sequenceLength745
species[Species:56210] Drosophila melanogaster
(referenceEntity)[EntityWithAccessionedSequence:206017] AXN [cytosol] [Drosophila melanogaster]
[EntityWithAccessionedSequence:206033] Phospho (multi-site) AXN [cytosol] [Drosophila melanogaster]
[EntityWithAccessionedSequence:206136] Phospho AXN [cytosol] [Drosophila melanogaster]
[EntityWithAccessionedSequence:206169] Phospho (3 sites) AXN [cytosol] [Drosophila melanogaster]
(referenceSequence)[ModifiedResidue:205765] O-phospho-L-threonine at 517
[ModifiedResidue:205854] O-phospho-L-serine at 529
[ModifiedResidue:206043] O-phospho-L-serine at 522
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No pathways have been reviewed or authored by UniProt:Q9V407 Axn (85721)