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Details on Person IPAF binds procaspase-1

Class:Id	Reaction:844617
_displayName	IPAF binds procaspase-1
_doRelease	TRUE
_timestamp	2014-07-07 23:01:11
authored	[InstanceEdit:622270] Jupe, S, 2010-04-22
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:844609] Jupe, S, 2010-05-28
edited	[InstanceEdit:1253354] Jupe, S, 2011-04-28
input	[EntityWithAccessionedSequence:448692] CASP1(1-404) [cytosol] [Homo sapiens] [Complex:877394] IPAF elicitors:NLRC4 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:873970] Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
modified	[InstanceEdit:844626] Jupe, S, 2010-05-28 [InstanceEdit:874056] Jupe, S, 2010-06-09 [InstanceEdit:874110] Jupe, S, 2010-06-10 [InstanceEdit:877390] Jupe, S, 2010-06-14 [InstanceEdit:918254] Jupe, S, 2010-08-02 [InstanceEdit:925457] Jupe, S, 2010-08-06 [InstanceEdit:1253356] Jupe, S, 2011-04-28 [InstanceEdit:1361857] Jupe, S, 2011-06-06 [InstanceEdit:1361865] Jupe, S, 2011-06-06 [InstanceEdit:5606958] Gillespie, Marc E, 2014-07-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IPAF binds procaspase-1
output	[Complex:874083] IPAF elicitors:NLRC4:Procaspase-1 [cytosol] [Homo sapiens]
precedingEvent	[BlackBoxEvent:874084] IPAF is activated [Homo sapiens] [BlackBoxEvent:6801415] TP53 stimulates NLRC4 expression [Homo sapiens]
relatedSpecies	[Species:451465] Salmonella typhimurium
releaseDate	2011-06-14
reviewed	[InstanceEdit:1253355] Kufer, TA, 2011-04-28 [InstanceEdit:1361863] Rittinger, K, 2011-06-06 [InstanceEdit:1361862] Wong, Edmond, 2011-06-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1357517] R-HSA-844617.2
summation	[Summation:918255] IPAF contains an N-terminal CARD domain, a central nucleotid...
(hasEvent)	[Pathway:844623] The IPAF inflammasome [Homo sapiens]
(precedingEvent)	[Reaction:448678] CTSG cleaves CASP1(1-404) [Homo sapiens]
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No pathways have been reviewed or authored by IPAF binds procaspase-1 (844617)