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Details on Person The snRNA activating protein complex (SNAPc) (Sadowski et al...

Class:IdSummation:83794
_displayNameThe snRNA activating protein complex (SNAPc) (Sadowski et al...
_timestamp2003-12-01 21:20:40
created[InstanceEdit:75942] Hernandez, N, 2003-09-11 07:42:29
literatureReference[LiteratureReference:83851] Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes
[LiteratureReference:83852] Identification of transcription factors required for the expression of mammalian U6 genes in vitro
[LiteratureReference:83859] Targeting TBP to a non-TATA box cis-regulatory element: a TBP-containing complex activates transcription from snRNA promoters through the PSE
modified[InstanceEdit:83823] Gillespie, ME, 2003-12-01 00:00:00
textThe snRNA activating protein complex (SNAPc) (Sadowski et al., 1993), the PSE binding protein (PBP) (Waldschmidt et al., 1991), or the PSE transcription factor (PTF) (Murphy et al., 1992). The complex contains five types of subunits and binds to the PSE. Type 3 promoters also recruit Brf2-TFIIIB through a combination of protein-protein contacts with SNAPc and a direct association of the TBP component of Brf2-TFIIIB with the TATA box. This then allows RNA polymerase III to join the complex.
(summation)[Reaction:83793] Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex [Homo sapiens]
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