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Details on Person UniProt:Q12789 GTF3C1
| Class:Id | ReferenceGeneProduct:83696 |
|---|---|
| _chainChangeLog | chain:1-2109 added on Fri February 6 2015 |
| _displayName | UniProt:Q12789 GTF3C1 |
| _timestamp | 2024-11-03 19:39:14 |
| chain | chain:1-2109 |
| checksum | 37A03135EFE695FC |
| comment | FUNCTION Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element.SUBUNIT Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6 (PubMed:19299493). Interacts with IGHMBP2. Interacts with MAF1 (PubMed:18377933).INTERACTION Belongs to the TFIIIC subunit 1 family.SEQUENCE CAUTION Contaminating sequence. Potential vector sequence at the N-terminus. |
| description | recommendedName: General transcription factor 3C polypeptide 1 alternativeName: TF3C-alpha alternativeName: TFIIIC box B-binding subunit alternativeName: Transcription factor IIIC 220 kDa subunit shortName: TFIIIC 220 kDa subunit shortName: TFIIIC220 alternativeName: Transcription factor IIIC subunit alpha |
| geneName | GTF3C1 |
| identifier | Q12789 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Alternative splicing Direct protein sequencing DNA-binding Isopeptide bond Nucleus Phosphoprotein Proteomics identification Reference proteome Transcription Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | GTF3C1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8996917] ENSEMBL:ENSG00000077235 GTF3C1 [Homo sapiens] |
| secondaryIdentifier | TF3C1_HUMAN B2RP21 Q12838 Q6DKN9 Q9Y4W9 |
| sequenceLength | 2109 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:154613] UniProt:Q12789-2 GTF3C1 [Homo sapiens] [ReferenceIsoform:251007] UniProt:Q12789-3 GTF3C1 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:83697] GTF3C1 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q12789 GTF3C1 (83696)
