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Details on Person UniProt:Q9Y5Q8 GTF3C5
| Class:Id | ReferenceGeneProduct:83692 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-519 added on Sat February 7 2015;initiator methionine:1 for 83692 removed on Fri Nov 03 2023;initiator methionine: for 83692 added on Fri Nov 03 2023;initiator methionine: for 83692 removed on Fri Aug 15 2025;initiator methionine:1 for 83692 added on Fri Aug 15 2025 |
| _displayName | UniProt:Q9Y5Q8 GTF3C5 |
| _timestamp | 2026-02-20 22:17:01 |
| chain | initiator methionine:1 chain:2-519 |
| checksum | 088B8B6125CEEF36 |
| comment | FUNCTION Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.SUBUNIT Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1, GTF3C6 and TBP.SUBCELLULAR LOCATION Belongs to the TFIIIC subunit 5 family. |
| description | recommendedName: General transcription factor 3C polypeptide 5 alternativeName: TF3C-epsilon alternativeName: Transcription factor IIIC 63 kDa subunit shortName: TFIIIC 63 kDa subunit shortName: TFIIIC63 alternativeName: Transcription factor IIIC subunit epsilon |
| geneName | GTF3C5 CDABP0017 |
| identifier | Q9Y5Q8 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Alternative splicing DNA-binding Nucleus Proteomics identification Reference proteome Transcription |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | GTF3C5 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8995743] ENSEMBL:ENSG00000148308 GTF3C5 [Homo sapiens] |
| secondaryIdentifier | TF3C5_HUMAN A6NI44 A6NJB9 Q5T7U2 Q5T7U3 Q8N2U7 Q8N857 Q96GD9 Q9H4P2 |
| sequenceLength | 519 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:154626] UniProt:Q9Y5Q8-2 GTF3C5 [Homo sapiens] [ReferenceIsoform:386235] UniProt:Q9Y5Q8-3 GTF3C5 [Homo sapiens] [ReferenceIsoform:416089] UniProt:Q9Y5Q8-1 GTF3C5 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:83693] GTF3C5 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9Y5Q8 GTF3C5 (83692)
