Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8

Class:Id	Reaction:83586
_displayName	FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8
_doRelease	TRUE
_timestamp	2016-11-10 00:55:25
authored	[InstanceEdit:140952] Gillespie, ME, 2004-08-24 21:33:15
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:110071] Tschopp, J�rg, 2004-01-28
figure	[Figure:141228] /figures/FasL_Fas_FADD_ProCaspase8.jpg
input	[Complex:43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:57031] CASP8(1-479) [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:140941] Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
modified	[InstanceEdit:83604] Matthews, L, 2003-11-23 12:20:00 [InstanceEdit:83669] Matthews, L, 0000-00-00 00:00:00 [InstanceEdit:83683] Matthews, L, 2003-11-27 03:00:00 [InstanceEdit:83892] Matthews, L, 2003-12-10 03:30:00 [InstanceEdit:109912] Joshi-Tope, G, 2004-01-21 22:18:55 [InstanceEdit:109917] Joshi-Tope, G, 2004-01-22 15:11:19 [InstanceEdit:110070] Joshi-Tope, G, 2004-01-28 14:40:07 [InstanceEdit:140952] Gillespie, ME, 2004-08-24 21:33:15 [InstanceEdit:141243] Gillespie, ME, 2004-09-07 03:33:39 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2648974] D'Eustachio, P, 2012-11-21 [InstanceEdit:3597633] Shamovsky, V, 2013-05-22 [InstanceEdit:5334691] Gillespie, Marc E, 2014-02-24 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8
output	[Complex:75114] FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:83650] FasL:Fas binds FADD [Homo sapiens] [Reaction:71050] Trimerization of the FASL:FAS receptor complex [Homo sapiens]
releaseDate	2004-10-27
reviewed	[InstanceEdit:3597630] Pop, Cristina, Salvesen, Guy S., 2013-05-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360537] R-HSA-83586.3
summation	[Summation:178764] Caspase-8 precursor (Pro-Caspase-8, also known as MACH) bind...
(hasEvent)	[Pathway:75157] FasL/ CD95L signaling [Homo sapiens]
(normalReaction)	[Reaction:5334739] HPV Suppressed FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 [Homo sapiens]
(precedingEvent)	[Reaction:73945] FAS-mediated dimerization of procaspase-8 [Homo sapiens] [Reaction:3465429] FLIP(S) and procaspase-8 form heterodimer [Homo sapiens] [Reaction:3465459] FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling [Homo sapiens] [Reaction:5675456] FLIP(L) and procaspase-8 form heterodimer [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9786502] Update Tracker - [Reaction:83586] FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 - v49:[removeRegulator] [_UpdateTracker:9787964] Update Tracker - [Reaction:83586] FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 - v44:[addRegulator] [_UpdateTracker:9788296] Update Tracker - [Reaction:83586] FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 - v43:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (83586)