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Details on Person Matthews, L, 2003-11-18 00:00:00

Class:Id	InstanceEdit:83535
_displayName	Matthews, L, 2003-11-18 00:00:00
_timestamp	2013-11-25 18:15:53
author	[Person:142011] Matthews, Lisa
dateTime	2003-11-18 05:00:00
modified	[InstanceEdit:5173293] Matthews, Lisa, 2013-11-25
(authored)	[Reaction:5693536] ATM phosphorylates MDC1 [Homo sapiens] [Pathway:5693548] Sensing of DNA Double Strand Breaks [Homo sapiens] [Reaction:5693551] Phosphorylation of BRCA1-A complex at multiple sites by ATM [Homo sapiens] [Pathway:5693565] Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks [Homo sapiens] [Reaction:5693583] MDC1 associates with gamma-H2AFX at nuclear foci [Homo sapiens] [Reaction:5693598] ATM phosphorylates NBN [Homo sapiens]
(created)	[CatalystActivity:83536] protein serine/threonine kinase activity of p-S1981-ATM [nucleoplasm] [Complex:83538] dimeric ATM kinase [nucleoplasm] [Homo sapiens] [Summation:83541] ATM is present in unirradiated cells as a dimer or higher-or... [Summation:83543] Detection of DNA double-strand breaks involves sensor protei... [Summation:83545] Following the detection of DSBs, ATM mediates the phosphoryl... [Summation:83548] Following exposure to ionizing radiation, a number of recomb... [Summation:83550] Homologous recombination repair of replication-dependent DNA... [ModifiedResidue:83555] O-phospho-L-serine at 343 [Summation:83558] NSB1 is a component of the MRE11/RAD50/NBS1 complex which ac... [Summation:83564] Recruitment of MDC1 to nuclear foci is mediated by H2AX. MDC... List all 20 refering instances
(modified)	[EntityWithAccessionedSequence:69484] ATM [nucleoplasm] [Homo sapiens] [Reaction:69891] Phosphorylation and activation of CHEK2 by ATM [Homo sapiens] [Pathway:73944] Recognition of Double-Strand Breaks by ATM [Homo sapiens] [Reaction:73946] Abortive initiation after formation of the first phosphodiester bond [Homo sapiens] [Reaction:73948] Ligation of DNA after branch migration [Homo sapiens] [Summation:73962] Double-strand breaks (DSBs), one of the most deleterious typ... [Summation:73964] The HRR pathway is an "error free" DNA repair mechanism that... [EntityWithAccessionedSequence:75145] p-S1981-ATM [nucleoplasm] [Homo sapiens] [Reaction:75146] TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 [Homo sapiens] [Pathway:75153] Apoptotic execution phase [Homo sapiens] List all 26 refering instances
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No pathways have been reviewed or authored by Matthews, L, 2003-11-18 00:00:00 (83535)