Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:A6QLQ8 ENDOU
| Class:Id | ReferenceGeneProduct:797610 |
|---|---|
| _chainChangeLog | signal peptide:1-18 added on Sat February 7 2015;chain:19-413 added on Sat February 7 2015 |
| _displayName | UniProt:A6QLQ8 ENDOU |
| _timestamp | 2025-02-21 18:36:19 |
| chain | signal peptide:1-18 chain:19-413 |
| checksum | ECBC928F474B51FB |
| comment | FUNCTION Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites. Targets mRNAs to regulate their expression (By similarity).CATALYTIC ACTIVITY ribonucleotidyl-uridine-RNA = a 5'-end dephospho-uridine-RNA + a 3'-end 2',3'-cyclophospho-ribonucleotide-RNACOFACTOR Monomer.SUBCELLULAR LOCATION Belongs to the ENDOU family. |
| created | [InstanceEdit:797602] Kanapin, AA |
| description | recommendedName: fullName evidence="5"Uridylate-specific endoribonuclease ecNumber evidence="4"3.1.-.- ecNumber evidence="1"4.6.1.- alternativeName: Protein endoU |
| geneName | ENDOU |
| identifier | A6QLQ8 |
| isSequenceChanged | FALSE |
| keyword | Disulfide bond Endonuclease Hydrolase Lyase Manganese Metal-binding Nuclease Reference proteome Repeat RNA-binding Secreted Signal |
| modified | [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9767224] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | ENDOU |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | ENDOU_BOVIN |
| sequenceLength | 413 |
| species | [Species:48898] Bos taurus |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:A6QLQ8 ENDOU (797610)
