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Details on Person The complete beta-oxidation spiral produces and consumes int...

Class:IdSummation:77404
_displayNameThe complete beta-oxidation spiral produces and consumes int...
_timestamp2004-01-02 22:05:50
created[InstanceEdit:77397] Gillespie, ME, 2003-10-25 00:00:00
literatureReference[LiteratureReference:109344] Metabolic functions of the two pathways of oleate beta-oxidation double bond metabolism during the beta-oxidation of oleic acid in rat heart mitochondria
[Book:77402] The Metabolic and Molecular Bases of Inherited Disease, 8th ed Scriver, CR Mitochondrial fatty acid oxidation disorders 0079130356
modified[InstanceEdit:109340] Gillespie, ME, 2004-01-02 00:00:00
textThe complete beta-oxidation spiral produces and consumes intermediates with a trans configuration. Mitochondrial beta-oxidation of unsaturated fatty acids leads to intermediates not compatible with the four enzymatic steps responsible for the beta-oxidation of saturated fatty acids. Unsaturated fatty acids that have bonds in the cis configuration require three separate enzymatic steps to prepare these molecules for the beta-oxidation pathway. The further processing of these intermediates requires additional enzymes, depending on the position of the double bonds in the original fatty acids. Described here is the beta-oxidation of linoleoyl-CoA.
(summation)[Pathway:77288] mitochondrial fatty acid beta-oxidation of unsaturated fatty acids [Homo sapiens]
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