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Details on Person Cytosolic fatty acid synthase (FAS) complex catalyzes the re...

Class:IdSummation:77381
_displayNameCytosolic fatty acid synthase (FAS) complex catalyzes the re...
_timestamp2024-03-19 22:28:36
created[InstanceEdit:77382] Joshi-Tope, G, 2003-10-23 17:11:00
modified[InstanceEdit:77453] Gopinathrao, G, 2007-03-20 09:37:59
[InstanceEdit:111311] Gopinathrao, G, 2004-02-12 12:01:08
[InstanceEdit:539120] D'Eustachio, P, 2010-03-09
[InstanceEdit:9865851] D'Eustachio, Peter, 2024-03-19
textCytosolic fatty acid synthase (FAS) complex catalyzes the reaction of acetyl-CoA with 7 malonyl-CoA and 14 NADHP + 14 H+ to form a molecule of palmitate and 7 CO2, 14 NADP+, 8 CoASH, and 6 H2O. The process proceeds via the successive condensations of malonyl groups onto the growing acyl chain,each followed by loss of CO2 and three steps of reduction (Jayakumar et al. 1995; Smith et al. 2003).
(summation)[Reaction:75872] Conversion of malonyl-CoA and acetyl-CoA to palmitate [Homo sapiens]
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