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Details on Person Octanoyl-CoA+FAD => trans-Oct-2-enoyl-CoA+FADH2

Class:Id	Reaction:77338
_displayName	Octanoyl-CoA+FAD => trans-Oct-2-enoyl-CoA+FADH2
_doRelease	TRUE
_timestamp	2025-12-30 14:35:01
catalystActivity	[CatalystActivity:77336] acyl-CoA dehydrogenase activity of ACADM tetramer [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:77247] Gillespie, ME, 2003-09-19 00:00:00
crossReference	[DatabaseIdentifier:9977722] RHEA:30944
input	[SimpleEntity:113596] FAD [mitochondrial matrix] [SimpleEntity:77337] Octanoyl-CoA [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix]
internalReviewed	[InstanceEdit:9978289] D'Eustachio, Peter, 2025-12-29
literatureReference	[LiteratureReference:77398] On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. II. The electron-transferring flavoprotein. [LiteratureReference:70739] Purification and properties of short chain acyl-CoA, medium chain acyl-CoA, and isovaleryl-CoA dehydrogenases from human liver
modified	[InstanceEdit:77397] Gillespie, ME, 2003-10-25 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9977727] D'Eustachio, Peter, 2025-12-22 [InstanceEdit:9978288] D'Eustachio, Peter, 2025-12-29 [InstanceEdit:9978313] D'Eustachio, Peter, 2025-12-30
name	Octanoyl-CoA+FAD => trans-Oct-2-enoyl-CoA+FADH2 octanoyl-CoA + FAD + H(+) => (2E)-octenoyl-CoA + FADH2
output	[SimpleEntity:31649] FADH2 [mitochondrial matrix] [SimpleEntity:77332] trans-Oct-2-enoyl-CoA [mitochondrial matrix]
precedingEvent	[Reaction:77340] 3-Oxodecanoyl-CoA+CoA-SH => Octanoyl-CoA + acetyl-CoA [Homo sapiens] [Reaction:77342] (S)-Hydroxydecanoyl-CoA+NAD => 3-Oxodecanoyl-CoA+NADH+H [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2004-07-06
reviewed	[InstanceEdit:9978314] D'Eustachio, Peter, 2025-12-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361817] R-HSA-77338.4
structureModified	[InstanceEdit:9977727] D'Eustachio, Peter, 2025-12-22
summation	[Summation:179006] ACADM in the mitochondrial matrix dehydrogenates octanoyl-Co...
(hasEvent)	[Pathway:77348] Beta oxidation of octanoyl-CoA to hexanoyl-CoA [Homo sapiens]
(precedingEvent)	[Reaction:77333] trans-Oct-2-enoyl-CoA+H2O => (S)-Hydroxyoctanoyl-CoA [Homo sapiens] [Reaction:169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9984652] Update Tracker - [Reaction:77338] Octanoyl-CoA+FAD => trans-Oct-2-enoyl-CoA+FADH2 - v96:[modifyText, removeInput]
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No pathways have been reviewed or authored by Octanoyl-CoA+FAD => trans-Oct-2-enoyl-CoA+FADH2 (77338)