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Details on Person (S)-3-Hydroxyhexadecanoyl-CoA+NAD => 3-Oxopalmitoyl-CoA+NADH+H

Class:Id	Reaction:77303
_displayName	(S)-3-Hydroxyhexadecanoyl-CoA+NAD => 3-Oxopalmitoyl-CoA+NADH+H
_doRelease	TRUE
_timestamp	2025-12-19 22:44:56
catalystActivity	[CatalystActivity:77282] (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity of Trifunctional Protein [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:77247] Gillespie, ME, 2003-09-19 00:00:00
crossReference	[DatabaseIdentifier:9977442] RHEA:31160
input	[SimpleEntity:77300] (S)-3-Hydroxyhexadecanoyl-CoA [mitochondrial matrix] [SimpleEntity:113526] NAD+ [mitochondrial matrix]
literatureReference	[LiteratureReference:77405] Human liver long-chain 3-hydroxyacyl-coenzyme A dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria.
modified	[InstanceEdit:77397] Gillespie, ME, 2003-10-25 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9977441] D'Eustachio, Peter, 2025-12-19
name	(S)-3-Hydroxyhexadecanoyl-CoA+NAD => 3-Oxopalmitoyl-CoA+NADH+H (3S)-hydroxyhexadecanoyl-CoA + NAD(+) => 3-oxohexadecanoyl-CoA + NADH + H(+)
output	[SimpleEntity:29362] NADH [mitochondrial matrix] [SimpleEntity:77302] 3-Oxopalmitoyl-CoA [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix]
precedingEvent	[Reaction:77301] trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA [Homo sapiens] [Reaction:77299] palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2 [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360722] R-HSA-77303.4
summation	[Summation:178248] Trifunctional protein in the mitochondrial matrix dehydrogen...
(hasEvent)	[Pathway:77305] Beta oxidation of palmitoyl-CoA to myristoyl-CoA [Homo sapiens]
(precedingEvent)	[Reaction:77304] 3-Oxopalmitoyl-CoA+CoA-SH => myristoyl-CoA+acetyl-CoA [Homo sapiens] [Reaction:163217] Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9984718] Update Tracker - [Reaction:77303] (S)-3-Hydroxyhexadecanoyl-CoA+NAD => 3-Oxopalmitoyl-CoA+NADH+H - v96:[modifyText]
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