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Details on Person palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2

Class:Id	Reaction:77299
_displayName	palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2
_doRelease	TRUE
_timestamp	2025-12-30 14:35:04
catalystActivity	[CatalystActivity:77280] acyl-CoA dehydrogenase activity of ACADVL dimer [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:77247] Gillespie, ME, 2003-09-19 00:00:00
crossReference	[DatabaseIdentifier:9977436] RHEA:43449
input	[SimpleEntity:77281] PalmCoA [mitochondrial matrix] [SimpleEntity:113596] FAD [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix]
internalReviewed	[InstanceEdit:9978289] D'Eustachio, Peter, 2025-12-29
literatureReference	[LiteratureReference:77398] On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. II. The electron-transferring flavoprotein. [LiteratureReference:77400] Beta-oxidation of long-chain fatty acids by human fibroblasts: evidence for a novel long-chain acyl-coenzyme A dehydrogenase.
modified	[InstanceEdit:77397] Gillespie, ME, 2003-10-25 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9977441] D'Eustachio, Peter, 2025-12-19 [InstanceEdit:9978288] D'Eustachio, Peter, 2025-12-29 [InstanceEdit:9978313] D'Eustachio, Peter, 2025-12-30
name	palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2 oxidized (electron-transfer flavoprotein) + hexadecanoyl-CoA + H(+) => (2E)-hexadecenoyl-CoA + reduced (electron-transfer flavoprotein)
output	[SimpleEntity:31649] FADH2 [mitochondrial matrix] [SimpleEntity:77284] trans-Hexadec-2-enoyl-CoA [mitochondrial matrix]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2004-07-06
reviewed	[InstanceEdit:9978314] D'Eustachio, Peter, 2025-12-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360527] R-HSA-77299.4
structureModified	[InstanceEdit:9977441] D'Eustachio, Peter, 2025-12-19
summation	[Summation:179029] VLCAD in the mitochondrial matrix dehydrogenates palmitoyl-C...
(hasEvent)	[Pathway:77305] Beta oxidation of palmitoyl-CoA to myristoyl-CoA [Homo sapiens]
(precedingEvent)	[Reaction:77301] trans-Hexadec-2-enoyl-CoA+H2O => (S)-3-Hydroxyhexadecanoyl-CoA [Homo sapiens] [Reaction:169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9984650] Update Tracker - [Reaction:77299] palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2 - v96:[modifyText, removeInput]
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No pathways have been reviewed or authored by palmitoyl-CoA+FAD => trans-Hexadec-2-enoyl-CoA+FADH2 (77299)