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Details on Person 2-trans-Dodecenoyl-CoA+H2O =>( S)-3-Hydroxydodecanoyl-CoA

Class:Id	Reaction:77256
_displayName	2-trans-Dodecenoyl-CoA+H2O =>( S)-3-Hydroxydodecanoyl-CoA
_doRelease	TRUE
_timestamp	2025-12-22 17:36:11
catalystActivity	[CatalystActivity:71049] enoyl-CoA hydratase activity of ECHS1 hexamer [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:77247] Gillespie, ME, 2003-09-19 00:00:00
crossReference	[DatabaseIdentifier:9977647] RHEA:31077
input	[SimpleEntity:113521] H2O [mitochondrial matrix] [SimpleEntity:77255] 2-trans-Dodecenoyl-CoA [mitochondrial matrix]
literatureReference	[LiteratureReference:77407] Enzymes of fatty acid metabolism. II. Properties of crystalline crotonase.
modified	[InstanceEdit:77397] Gillespie, ME, 2003-10-25 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9977654] D'Eustachio, Peter, 2025-12-22
name	2-trans-Dodecenoyl-CoA+H2O =>( S)-3-Hydroxydodecanoyl-CoA 2E)-dodecenoyl-CoA + H2O => (3S)-3-hydroxydodecanoyl-CoA
output	[SimpleEntity:77252] (S)-3-Hydroxydodecanoyl-CoA [mitochondrial matrix]
precedingEvent	[Reaction:77263] lauroyl-CoA+FAD => 2-trans-Dodecenoyl-CoA+FADH2 [Homo sapiens] [Reaction:77271] 3-Oxotetradecanoyl-CoA+CoA-SH => Lauroyl-CoA + acetyl-CoA [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360391] R-HSA-77256.4
summation	[Summation:178333] ECHS1 in the mitochondrial matrix hydrates trans-dodec-2-eno...
(hasEvent)	[Pathway:77310] Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA [Homo sapiens]
(precedingEvent)	[Reaction:77254] (S)-3-Hydroxydodecanoyl-CoA+NAD => 3-Oxododecanoyl-CoA+NADH+H [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9984623] Update Tracker - [Reaction:77256] 2-trans-Dodecenoyl-CoA+H2O =>( S)-3-Hydroxydodecanoyl-CoA - v96:[modifyText]
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No pathways have been reviewed or authored by 2-trans-Dodecenoyl-CoA+H2O =>( S)-3-Hydroxydodecanoyl-CoA (77256)