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Details on Person (S)-3-Hydroxydodecanoyl-CoA+NAD => 3-Oxododecanoyl-CoA+NADH+H

Class:Id	Reaction:77254
_displayName	(S)-3-Hydroxydodecanoyl-CoA+NAD => 3-Oxododecanoyl-CoA+NADH+H
_doRelease	TRUE
_timestamp	2025-12-22 17:36:06
catalystActivity	[CatalystActivity:71061] (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity of HADH dimer [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:77247] Gillespie, ME, 2003-09-19 00:00:00
crossReference	[DatabaseIdentifier:9977649] RHEA:31180
input	[SimpleEntity:113526] NAD+ [mitochondrial matrix] [SimpleEntity:77252] (S)-3-Hydroxydodecanoyl-CoA [mitochondrial matrix]
literatureReference	[LiteratureReference:77409] Human short-chain L-3-hydroxyacyl-CoA dehydrogenase: cloning and characterization of the coding sequence.
modified	[InstanceEdit:77397] Gillespie, ME, 2003-10-25 00:00:00 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9977654] D'Eustachio, Peter, 2025-12-22
name	(S)-3-Hydroxydodecanoyl-CoA+NAD => 3-Oxododecanoyl-CoA+NADH+H (3S)-3-hydroxydodecanoyl-CoA + NAD(+) => 3-oxododecanoyl-CoA + NADH + H(+)
output	[SimpleEntity:29362] NADH [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix] [SimpleEntity:77253] 3-Oxododecanoyl-CoA [mitochondrial matrix]
precedingEvent	[Reaction:77256] 2-trans-Dodecenoyl-CoA+H2O =>( S)-3-Hydroxydodecanoyl-CoA [Homo sapiens] [Reaction:77263] lauroyl-CoA+FAD => 2-trans-Dodecenoyl-CoA+FADH2 [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361547] R-HSA-77254.4
summation	[Summation:178247] HADH in the mitochondrial matrix dehydrogenates (S)-3-hydrox...
(hasEvent)	[Pathway:77310] Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA [Homo sapiens]
(precedingEvent)	[Reaction:77309] 3-Oxododecanoyl-CoA+CoA-SH => Decanoyl-CoA + acetyl-CoA [Homo sapiens] [Reaction:163217] Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9984694] Update Tracker - [Reaction:77254] (S)-3-Hydroxydodecanoyl-CoA+NAD => 3-Oxododecanoyl-CoA+NADH+H - v96:[modifyText]
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No pathways have been reviewed or authored by (S)-3-Hydroxydodecanoyl-CoA+NAD => 3-Oxododecanoyl-CoA+NADH+H (77254)