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Details on Person Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme

Class:Id	Reaction:77078
_displayName	Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme
_doRelease	TRUE
_timestamp	2016-11-10 00:54:59
authored	[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
catalystActivity	[CatalystActivity:77052] polynucleotide 5'-phosphatase activity of Capping complex (initial) [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
figure	[Figure:77485] /figures/Cap1a.jpg
input	[Complex:77063] Capping complex (initial) [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:77482] Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme.
modified	[InstanceEdit:77367] Joshi-Tope, G, 2003-10-17 16:16:00 [InstanceEdit:77479] Gopinathrao, G, 2003-10-29 09:19:11 [InstanceEdit:111340] Gopinathrao, G, 2004-02-12 15:30:00 [InstanceEdit:113653] Schmidt, EE, 2004-06-14 05:50:20 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:167005] Schmidt, EE, 2005-10-10 15:17:32 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme
output	[Complex:77064] Capping complex (hydrolyzed) [nucleoplasm] [Homo sapiens] [SimpleEntity:113550] Pi [nucleoplasm]
precedingEvent	[Reaction:77077] Capping complex formation [Homo sapiens] [Reaction:77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360851] R-HSA-77078.3
summation	[Summation:77079] After the capping complex is formed, the RNA triphosphatase ...
(hasEvent)	[Pathway:72086] mRNA Capping [Homo sapiens]
(inferredFrom)	[Reaction:167400] Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme [Homo sapiens] [Reaction:1113201] Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme [Oryza sativa]
(orthologousEvent)	[Reaction:1113201] Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme [Oryza sativa]
(precedingEvent)	[Reaction:77081] Formation of the CE:GMP intermediate complex [Homo sapiens]
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