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Details on Person SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)

Class:IdReaction:77073
_displayNameSPT5 subunit of Pol II binds the RNA triphosphatase (RTP)
_doReleaseTRUE
_timestamp2026-05-14 23:31:00
authored[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
input[Complex:77056] RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:3009372] p-SUPT5H [nucleoplasm] [Homo sapiens]
[Complex:9989096] RNMT:RAMAC [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9989102] D'Eustachio, Peter, 2026-05-14
literatureReference[LiteratureReference:6787501] Cap-binding complex (CBC)
modified[InstanceEdit:77027] Gopinathrao, G, 2003-10-15 15:18:37
[InstanceEdit:113792] Gopinathrao, G, 2004-06-22 14:12:50
[InstanceEdit:157183] Joshi-Tope, G, 2004-12-16 23:59:50
[InstanceEdit:159379] Gopinathrao, G, 2005-03-07 18:29:36
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:350781] Gopinathrao, G, 2008-05-20 17:45:26
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:3009364] Jassal, B, 2013-02-05
[InstanceEdit:6787528] D'Eustachio, Peter, 2015-07-14
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9989093] D'Eustachio, Peter, 2026-05-14
[InstanceEdit:9989103] D'Eustachio, Peter, 2026-05-14
[InstanceEdit:9989105] D'Eustachio, Peter, 2026-05-14
nameSPT5 subunit of Pol II binds the RNA triphosphatase (RTP)
output[Complex:77061] CE:Pol II CTD:Spt5 complex [nucleoplasm] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2004-07-06
reviewed[InstanceEdit:9989106] Hill, David P, 2026-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359990] R-HSA-77073.4
structureModified[InstanceEdit:9989093] D'Eustachio, Peter, 2026-05-14
summation[Summation:77074] The capping enzyme interacts with the Spt5 subunit of trans...
(hasEvent)[Pathway:72086] mRNA Capping [Homo sapiens]
[Pathway:77075] RNA Pol II CTD phosphorylation and interaction with CE [Homo sapiens]
(inferredFrom)[Reaction:167153] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) [Homo sapiens]
[Reaction:1113185] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) [Oryza sativa]
(orthologousEvent)[Reaction:1113185] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) [Oryza sativa]
(precedingEvent)[Reaction:77077] Capping complex formation [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780903] Update Tracker - [Reaction:77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - v61:[modifyText]
[_UpdateTracker:9784238] Update Tracker - [Reaction:77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - v54:[addLiteratureReference, modifyText]
[_UpdateTracker:9784587] Update Tracker - [Reaction:77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - v53:[modifyText]
[_UpdateTracker:9787987] Update Tracker - [Reaction:77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - v44:[add_removeInput]
[_UpdateTracker:9789620] Update Tracker - [Reaction:77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - v37:[modifyText]
[_UpdateTracker:9791814] Update Tracker - [Reaction:77073] SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) - v25:[add_removeInput]
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