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Details on Person Ethylene is oxidized to Ethylene oxide by CYP1A1

Class:IdReaction:76472
_displayNameEthylene is oxidized to Ethylene oxide by CYP1A1
_doReleaseTRUE
_timestamp2018-10-19 12:17:54
authored[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
catalystActivity[CatalystActivity:76471] monooxygenase activity of CYP1A1 [endoplasmic reticulum membrane]
compartment[Compartment:12045] endoplasmic reticulum membrane
[Compartment:17957] endoplasmic reticulum lumen
[Compartment:17960] smooth endoplasmic reticulum
created[InstanceEdit:76326] Jassal, B, 2003-08-05 00:00:00
edited[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
goBiologicalProcess[GO_BiologicalProcess:3350] ethylene metabolic process
input[SimpleEntity:38985] C2H4 [endoplasmic reticulum lumen]
[SimpleEntity:113534] O2 [endoplasmic reticulum lumen]
[SimpleEntity:113601] NADPH [endoplasmic reticulum lumen]
[SimpleEntity:156540] H+ [endoplasmic reticulum lumen]
literatureReference[LiteratureReference:211842] Cytochrome P450 oxidations in the generation of reactive electrophiles: epoxidation and related reactions
[LiteratureReference:140966] Destruction of cytochrome P-450 by ethylene. Structure of the resulting prosthetic heme adduct.
modified[InstanceEdit:113653] Schmidt, EE, 2004-06-14 05:50:20
[InstanceEdit:139962] Jassal, B, 2004-08-11 05:47:32
[InstanceEdit:140961] Jassal, B, 2004-08-25 10:59:57
[InstanceEdit:141062] Jassal, B, 2004-08-27 04:15:09
[InstanceEdit:156525] Jassal, B, 2004-11-18 15:03:00
[InstanceEdit:156539] Jassal, B, 2004-11-19 09:05:24
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:211785] Jassal, B, 2008-02-08 15:20:09
[InstanceEdit:211841] Jassal, B, 2008-02-08 15:28:37
[InstanceEdit:350661] Jassal, Bijay, 2008-05-20
[InstanceEdit:351778] Jassal, Bijay, 2008-05-28
[InstanceEdit:352324] Jassal, B, 2008-06-02 12:56:30
[InstanceEdit:2656455] D'Eustachio, P, 2012-11-23
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9625155] Jassal, Bijay, 2018-10-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameEthylene is oxidized to Ethylene oxide by CYP1A1
Ethylene oxidized to Ethylene oxide
output[SimpleEntity:38987] EtO [endoplasmic reticulum lumen]
[SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
[SimpleEntity:113564] NADP+ [endoplasmic reticulum lumen]
regulatedBy[PositiveRegulation:8941462] Positive regulation by 'AHR:TCDD:ARNT [nucleoplasm]'
[NegativeRegulation:9625154] Negative regulation by 'AHRR:ARNT [nucleoplasm]'
releaseDate2008-06-30
reviewed[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:362007] R-HSA-76472.4
summation[Summation:141066] A simple example of epoxidation is the oxidation of an alken...
(hasEvent)[Pathway:211981] Xenobiotics [Homo sapiens]
(precedingEvent)[Reaction:176059] GST trimers transfer GS from GSH to luminal substrates [Homo sapiens]
(updatedInstance)[_UpdateTracker:9778743] Update Tracker - [Reaction:76472] Ethylene is oxidized to Ethylene oxide by CYP1A1 - v67:[addRegulator]
[_UpdateTracker:9782053] Update Tracker - [Reaction:76472] Ethylene is oxidized to Ethylene oxide by CYP1A1 - v59:[addRegulator]
[_UpdateTracker:9792052] Update Tracker - [Reaction:76472] Ethylene is oxidized to Ethylene oxide by CYP1A1 - v24:[add_removeLiteratureReference, modifyText]
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