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Details on Person CYP4A11 omega-hydroxylates DDCX

Class:Id	Reaction:76466
_displayName	CYP4A11 omega-hydroxylates DDCX
_doRelease	TRUE
_timestamp	2025-11-05 09:47:15
authored	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
catalystActivity	[CatalystActivity:76465] monooxygenase activity of Cytochrome P450 (CYP4A11 based) [endoplasmic reticulum membrane]
compartment	[Compartment:17960] smooth endoplasmic reticulum
created	[InstanceEdit:76326] Jassal, B, 2003-08-05 00:00:00
edited	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
goBiologicalProcess	[GO_BiologicalProcess:534] fatty acid metabolic process
input	[SimpleEntity:33549] DDCX [endoplasmic reticulum lumen] [SimpleEntity:113534] O2 [endoplasmic reticulum lumen] [SimpleEntity:113601] NADPH [endoplasmic reticulum lumen] [SimpleEntity:156540] H+ [endoplasmic reticulum lumen]
literatureReference	[LiteratureReference:211851] Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes
modified	[InstanceEdit:113653] Schmidt, EE, 2004-06-14 05:50:20 [InstanceEdit:156525] Jassal, B, 2004-11-18 15:03:00 [InstanceEdit:156539] Jassal, B, 2004-11-19 09:05:24 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:211787] Jassal, B, 2008-02-08 15:20:19 [InstanceEdit:211852] Jassal, B, 2008-02-08 15:33:23 [InstanceEdit:215093] Jassal, B, 2008-02-27 09:24:02 [InstanceEdit:350661] Jassal, Bijay, 2008-05-20 [InstanceEdit:351777] Jassal, B, 2008-05-28 08:44:17 [InstanceEdit:352324] Jassal, B, 2008-06-02 12:56:30 [InstanceEdit:5602279] Jassal, Bijay, 2014-06-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9971234] Stephan, Ralf, 2025-11-05
name	CYP4A11 omega-hydroxylates DDCX dodecanoic acid + O₂ + NADPH + H⁺ -> 12-hydroxydodecanoic acid + H₂O + NADP⁺
output	[SimpleEntity:42373] 12OH-DDCX [endoplasmic reticulum lumen] [SimpleEntity:113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:113564] NADP+ [endoplasmic reticulum lumen]
releaseDate	2008-06-30
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5602271] Jassal, Bijay, 2014-06-23
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361586] R-HSA-76466.3
summation	[Summation:156527] Dodecanoic acid (DDCX aka lauric acid) is a medium-chain fat...
(hasEvent)	[Pathway:211935] Fatty acids [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9786046] Update Tracker - [Reaction:76466] CYP4A11 12-hydroxylates DDCX - v50:[modifyText] [_UpdateTracker:9792057] Update Tracker - [Reaction:76466] CYP4A11 12-hydroxylates DDCX - v24:[add_removeLiteratureReference, modifyText]
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No pathways have been reviewed or authored by CYP4A11 omega-hydroxylates DDCX (76466)