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Details on Person RNA Polymerase II Promoter Opening: First Transition

Class:IdReaction:75949
_displayNameRNA Polymerase II Promoter Opening: First Transition
_doReleaseTRUE
_timestamp2021-08-03 16:34:23
authored[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
catalystActivity[CatalystActivity:109879] 3'-5' DNA helicase activity of TFIIH [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
edited[InstanceEdit:165073] Joshi-Tope, G, 0000-00-00 00:00:00
input[Complex:109635] pol II closed pre-initiation complex [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
literatureReference[LiteratureReference:111269] Polymerase II promoter activation: closed complex formation and ATP-driven start site opening.
[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
[LiteratureReference:110388] Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II.
[LiteratureReference:111270] DNA topology and a minimal set of basal factors for transcription by RNA polymerase II.
[LiteratureReference:111271] Peeling by binding or twisting by cranking: models for promoter opening and transcription initiation by RNA polymerase II.
[LiteratureReference:110385] The general transcription factors of RNA polymerase II.
[LiteratureReference:111272] Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7
[LiteratureReference:111273] Mechanism of RNA polymerase II--specific initiation of transcription in vitro: ATP requirement and uncapped runoff transcripts.
modified[InstanceEdit:76045] Joshi-Tope, G, 2003-09-22 12:25:00
[InstanceEdit:109692] Joshi-Tope, G, 2004-01-19 22:47:00
[InstanceEdit:109874] Joshi-Tope, G, 2004-01-21 14:30:42
[InstanceEdit:110067] Joshi-Tope, G, 2004-01-27 08:10:00
[InstanceEdit:110069] Joshi-Tope, G, 2004-01-27 22:51:03
[InstanceEdit:110383] Joshi-Tope, G, 2004-01-31 10:57:46
[InstanceEdit:110397] Joshi-Tope, G, 2004-01-31 13:46:17
[InstanceEdit:110751] Joshi-Tope, G, 2004-02-06 00:05:56
[InstanceEdit:111259] Joshi-Tope, G, 2004-02-11 09:36:36
[InstanceEdit:111441] Joshi-Tope, G, 2004-02-17 20:03:04
[InstanceEdit:113517] Schmidt, EE, 2004-06-09 05:19:12
[InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51
[InstanceEdit:167005] Schmidt, EE, 2005-10-10 15:17:32
[InstanceEdit:2671734] D'Eustachio, P, 2012-11-23
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9749431] Matthews, Lisa, 2021-08-03
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRNA Polymerase II Promoter Opening: First Transition
output[Complex:109876] pol II open pre-initiation complex [nucleoplasm] [Homo sapiens]
[SimpleEntity:113582] ADP [nucleoplasm]
[SimpleEntity:113550] Pi [nucleoplasm]
precedingEvent
releaseDate2004-07-06
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:362037] R-HSA-75949.4
summation[Summation:75950] After assembly of the complete RNA polymerase II-preinitiati...
(hasEvent)[Pathway:76042] RNA Polymerase II Transcription Initiation And Promoter Clearance [Homo sapiens]
(inferredFrom)[Reaction:167097] HIV Promoter Opening: First Transition [Homo sapiens]
[Reaction:1113167] RNA Polymerase II Promoter Opening: First Transition [Oryza sativa]
(orthologousEvent)[Reaction:1113167] RNA Polymerase II Promoter Opening: First Transition [Oryza sativa]
(precedingEvent)[Reaction:75861] NTP Binds Active Site of RNA Polymerase II [Homo sapiens]
[Reaction:75862] Fall Back to Closed Pre-initiation Complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9782677] Update Tracker - [Reaction:75949] RNA Polymerase II Promoter Opening: First Transition - v59:[modifyText]
[_UpdateTracker:9789625] Update Tracker - [Reaction:75949] RNA Polymerase II Promoter Opening: First Transition - v37:[modifyText]
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