Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person XRCC4:LIG4 [nucleoplasm]

Class:IdComplex:75912
_displayNameXRCC4:LIG4 [nucleoplasm]
_timestamp2015-04-06 20:55:01
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:75904] Matthews, L, 2003-09-07 08:47:00
hasComponent
literatureReference[LiteratureReference:5687173] Crystal structure of an Xrcc4-DNA ligase IV complex
modified[InstanceEdit:112172] Matthews, L, 0000-00-00 00:00:00
[InstanceEdit:113515] Schmidt, EE, 2004-06-07 04:20:06
[InstanceEdit:5687202] Orlic-Milacic, Marija, 2015-04-06
nameXRCC4:LIG4
XRCC4:DNA ligase IV complex
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:370366] R-HSA-75912.1
(hasComponent)[Complex:75915] DNA-PK:XRCC4:DNA ligase IV:DNA complex associated with ligatable DNA ends [nucleoplasm] [Homo sapiens]
[Complex:175440] viral DNA:Ku proteins:XRCC4:DNA ligase IV complex [nucleoplasm] [Homo sapiens]
[Complex:177529] 2-LTR circle formed in PIC [nucleoplasm] [Human immunodeficiency virus 1]
[Complex:5687362] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Extended ligatable DNA DSB ends [nucleoplasm] [Homo sapiens]
[Complex:5693617] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:Ligatable DNA DSB ends [nucleoplasm] [Homo sapiens]
[Complex:9979943] p-T2609,S2612,T2638,T2647-PRKDC:XRCC5:XRCC6:p-S516,S645-DCLRE1C:XRCC4:LIG4:NHEJ1:POLL,POLM:HHV8 linear DNA with extended ligatable ends [nucleoplasm] [Homo sapiens]
(hasMember)[CandidateSet:9980180] XRCC4:LIG4, (LIG3:XRCC1, LIG1) [nucleoplasm] [Human herpesvirus 8]
(input)[Reaction:175177] Association of XRCC4:DNA ligase IV complex with viral DNA ends [Homo sapiens]
[Reaction:5693574] XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ [Homo sapiens]
(output)[Reaction:175258] 2-LTR formation due to circularization of viral DNA [Homo sapiens]
[Reaction:5693604] XRCC4:LIG4 ligates DNA DSB ends during NHEJ [Homo sapiens]
(updatedInstance)[_UpdateTracker:9892389] Update Tracker - [Complex:75912] XRCC4:LIG4 [nucleoplasm] - v53:[addLiteratureReference, addName, add_removeHasComponent]
[Change default viewing format]
No pathways have been reviewed or authored by XRCC4:LIG4 [nucleoplasm] (75912)