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Details on Person 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]

Class:Id	Reaction:75900
_displayName	1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1]
_doRelease	TRUE
_timestamp	2016-11-10 00:54:33
catalystActivity	[CatalystActivity:76102] diacylglycerol O-acyltransferase activity of DGAT1 tetramer [endoplasmic reticulum membrane]
catalystActivityReference	[CatalystActivityReference:9643660] diacylglycerol O-acyltransferase activity of DGAT1 tetramer [endoplasmic reticulum membrane] Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:75111] Gopinathrao, G, 2003-09-07 15:00:00
input	[SimpleEntity:76103] DAG [cytosol] [SimpleEntity:75967] FACoA [cytosol]
literatureReference	[LiteratureReference:200098] Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein
modified	[InstanceEdit:76100] Gopinathrao, G, 2003-03-10 00:00:00 [InstanceEdit:76562] Gopinathrao, G, 2003-10-10 10:53:18 [InstanceEdit:77375] Joshi-Tope, G, 2003-10-22 08:20:00 [InstanceEdit:162611] Gopinathrao, G, 2005-04-01 19:07:46 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:200032] D'Eustachio, P, 2007-07-13 20:48:01 [InstanceEdit:428109] D'Eustachio, P, 2009-07-01 [InstanceEdit:549159] D'Eustachio, P, 2010-03-17 [InstanceEdit:549172] D'Eustachio, P, 2010-03-17 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] Conversion of Diacylglycerol to Triacylglycerol [DGAT1]
output	[SimpleEntity:549167] TAG [cytosol] [SimpleEntity:76194] CoA-SH [cytosol]
precedingEvent	[Reaction:75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate [Homo sapiens] [Reaction:75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360646] R-HSA-75900.4
summation	[Summation:178558] Tetrameric diacylglycerol O-acyltransferase 1 (DGAT1) associ...
(hasEvent)	[Pathway:75109] Triglyceride biosynthesis [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790473] Update Tracker - [Reaction:75900] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] - v33:[add_removeOutput, modifyText] [_UpdateTracker:9792336] Update Tracker - [Reaction:75900] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] - v22:[addLiteratureReference]
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No pathways have been reviewed or authored by 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (75900)