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Details on Person DHRS7B reduces GO3P to HXDG3P

Class:Id	Reaction:75883
_displayName	DHRS7B reduces GO3P to HXDG3P
_doRelease	TRUE
_timestamp	2019-03-29 21:35:33
authored	[InstanceEdit:398115] D'Eustachio, P, 2009-03-16 18:50:14
catalystActivity	[CatalystActivity:76162] acylglycerone-phosphate reductase (NADP+) activity of DHRS7B [peroxisomal membrane]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:75111] Gopinathrao, G, 2003-09-07 15:00:00
input	[SimpleEntity:70106] H+ [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:75973] GO3P [cytosol]
literatureReference	[LiteratureReference:390424] Purification and properties of acyl/alkyl dihydroxyacetone-phosphate reductase from guinea pig liver peroxisomes [LiteratureReference:9640566] Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARγ activation to decrease diet-induced obesity
modified	[InstanceEdit:76100] Gopinathrao, G, 2003-03-10 00:00:00 [InstanceEdit:76562] Gopinathrao, G, 2003-10-10 10:53:18 [InstanceEdit:77375] Joshi-Tope, G, 2003-10-22 08:20:00 [InstanceEdit:77382] Joshi-Tope, G, 2003-10-23 17:11:00 [InstanceEdit:77453] Gopinathrao, G, 2007-03-20 09:37:59 [InstanceEdit:77456] Gopinathrao, G, 2003-10-28 18:31:48 [InstanceEdit:77576] Gopinathrao, G, 2003-10-31 11:42:51 [InstanceEdit:111311] Gopinathrao, G, 2004-02-12 12:01:08 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:390413] D'Eustachio, P, 2009-02-06 21:28:38 [InstanceEdit:392205] D'Eustachio, P, 2009-02-27 15:50:55 [InstanceEdit:398114] D'Eustachio, P, 2009-03-16 18:51:20 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9640572] D'Eustachio, Peter, 2019-03-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	DHRS7B reduces GO3P to HXDG3P O-hexadecylglycerone phosphate + NADPH + H+ => 1-hexadecyl glycerol-3-phosphate + NADP+ Conversion of acylated DHAP to lysophosphatidic acid
output	[SimpleEntity:390422] HXDG3P [cytosol] [SimpleEntity:29366] NADP+ [cytosol]
precedingEvent	[BlackBoxEvent:390402] Movement of O-hexadecylglycerone phosphate from the peroxisomal matrix to the cytosol [Homo sapiens] [Reaction:390427] 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate [Homo sapiens]
releaseDate	2004-07-06
reviewed	[InstanceEdit:392190] Jassal, Bijay, 2009-02-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:359217] R-HSA-75883.4
summation	[Summation:178557] DHRS7B (Dehydrogenase/reductase SDR family member 7B) cataly...
(hasEvent)	[Pathway:75896] Plasmalogen biosynthesis [Homo sapiens]
(precedingEvent)	[Reaction:75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9777716] Update Tracker - [Reaction:75883] DHRS7B reduces GO3P to HXDG3P - v69:[addLiteratureReference, modifyText] [_UpdateTracker:9791634] Update Tracker - [Reaction:75883] DHRS7B reduces GO3P to HXDG3P - v28:[addInput, addLiteratureReference, add_removeOutput, modifyText]
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