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Details on Person Addition of the fourth nucleotide on the Nascent Transcript: Second Transition
Class:Id BlackBoxEvent:75869
_displayName Addition of the fourth nucleotide on the Nascent Transcript: Second Transition
_doRelease TRUE
_timestamp 2021-11-03 19:57:52
authored [InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
catalystActivity [CatalystActivity:109910] DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
edited [InstanceEdit:165073] Joshi-Tope, G, 0000-00-00 00:00:00
input [Complex:75878] pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] [Homo sapiens] [SimpleEntity:9757634] NTP [nucleoplasm]
literatureReference [LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation. [LiteratureReference:111262] Translocation after synthesis of a four-nucleotide RNA commits RNA polymerase II to promoter escape.
modified [InstanceEdit:76212] Gopinathrao, G, 2003-10-03 00:00:00 [InstanceEdit:76562] Gopinathrao, G, 2003-10-10 10:53:18 [InstanceEdit:77379] Joshi-Tope, G, 2003-10-23 15:19:00 [InstanceEdit:77382] Joshi-Tope, G, 2003-10-23 17:11:00 [InstanceEdit:110067] Joshi-Tope, G, 2004-01-27 08:10:00 [InstanceEdit:110069] Joshi-Tope, G, 2004-01-27 22:51:03 [InstanceEdit:110383] Joshi-Tope, G, 2004-01-31 10:57:46 [InstanceEdit:111172] Joshi-Tope, G, 2004-02-09 11:58:07 [InstanceEdit:111259] Joshi-Tope, G, 2004-02-11 09:36:36 [InstanceEdit:111441] Joshi-Tope, G, 2004-02-17 20:03:04 [InstanceEdit:113400] Gopinathrao, G, 2004-05-06 22:00:00 [InstanceEdit:159941] Gopinathrao, G, 2005-03-21 18:52:55 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:167003] Schmidt, EE, 2005-10-10 13:46:51 [InstanceEdit:194432] Schmidt, EE, 2007-03-13 12:36:16 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9613503] Gillespie, Marc E, 2018-07-13 [InstanceEdit:9757681] D'Eustachio, Peter, 2021-11-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Addition of the fourth nucleotide on the Nascent Transcript: Second Transition
output [Complex:75881] pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:65888] GTF2B [nucleoplasm] [Homo sapiens] [SimpleEntity:113541] PPi [nucleoplasm]
precedingEvent
releaseDate 2004-07-06
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:360781] R-HSA-75869.5
summation [Summation:111274] Formation of the third phosphodiester bond creates a 4-nt p...
(hasEvent) [Pathway:73776] RNA Polymerase II Promoter Escape [Homo sapiens]
(inferredFrom) [BlackBoxEvent:167113] Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition [Homo sapiens] [BlackBoxEvent:1113044] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition [Oryza sativa]
(orthologousEvent) [BlackBoxEvent:1113044] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition [Oryza sativa]
(precedingEvent) [Reaction:75856] Abortive Initiation Before Second Transition [Homo sapiens] [Reaction:75873] Addition of Nucleotides 5 through 9 on the growing Transcript [Homo sapiens]
(updatedInstance) [_UpdateTracker:9775477] Update Tracker - [BlackBoxEvent:75869] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition - v79:[add_removeInput] [_UpdateTracker:9779103] Update Tracker - [BlackBoxEvent:75869] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition - v66:[removeCatalystActivity] [_UpdateTracker:9784082] Update Tracker - [BlackBoxEvent:75869] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition - v54:[modifyText] [_UpdateTracker:9784654] Update Tracker - [BlackBoxEvent:75869] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition - v53:[modifyText] [_UpdateTracker:9789870] Update Tracker - [BlackBoxEvent:75869] Addition of the fourth nucleotide on the Nascent Transcript: Second Transition - v37:[modifyText]
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