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Details on Person NTP Binds Active Site of RNA Polymerase II

Class:Id	Reaction:75861
_displayName	NTP Binds Active Site of RNA Polymerase II
_doRelease	TRUE
_timestamp	2021-11-03 19:58:05
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
input	[Complex:109876] pol II open pre-initiation complex [nucleoplasm] [Homo sapiens] [SimpleEntity:9757634] NTP [nucleoplasm] [SimpleEntity:9757634] NTP [nucleoplasm]
literatureReference	[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
modified	[InstanceEdit:76212] Gopinathrao, G, 2003-10-03 00:00:00 [InstanceEdit:76562] Gopinathrao, G, 2003-10-10 10:53:18 [InstanceEdit:77377] Joshi-Tope, G, 2003-10-23 01:03:03 [InstanceEdit:77379] Joshi-Tope, G, 2003-10-23 15:19:00 [InstanceEdit:110066] Joshi-Tope, G, 2004-01-26 13:16:45 [InstanceEdit:110751] Joshi-Tope, G, 2004-02-06 00:05:56 [InstanceEdit:113852] Joshi-Tope, G, 2004-06-23 21:17:01 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:2671734] D'Eustachio, P, 2012-11-23 [InstanceEdit:6787507] D'Eustachio, Peter, 2015-07-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9757681] D'Eustachio, Peter, 2021-11-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NTP Binds Active Site of RNA Polymerase II
output	[Complex:83551] Pol II initiation complex [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:75949] RNA Polymerase II Promoter Opening: First Transition [Homo sapiens] [Reaction:109639] Formation of the closed pre-initiation complex [Homo sapiens]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360514] R-HSA-75861.5
summation	[Summation:178999] At the beginning of this reaction, 1 molecule of 'pol II ope...
(hasEvent)	[Pathway:75953] RNA Polymerase II Transcription Initiation [Homo sapiens]
(inferredFrom)	[Reaction:167118] NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex [Homo sapiens] [Reaction:1113122] NTP Binds Active Site of RNA Polymerase II [Oryza sativa]
(orthologousEvent)	[Reaction:1113122] NTP Binds Active Site of RNA Polymerase II [Oryza sativa]
(precedingEvent)	[Reaction:75866] Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775467] Update Tracker - [Reaction:75861] NTP Binds Active Site of RNA Polymerase II - v79:[add_removeInput] [_UpdateTracker:9784152] Update Tracker - [Reaction:75861] NTP Binds Active Site of RNA Polymerase II - v54:[addLiteratureReference]
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